{{Rsnum
|rsid=2786098
|Gene=CRB1
|Chromosome=1
|position=197356778
|Orientation=minus
|GMAF=0.1965
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=CRB1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 7.1 | 32.7 | 60.2
| HCB | 5.8 | 35.8 | 58.4
| JPT | 6.2 | 31.9 | 61.9
| YRI | 0.0 | 8.8 | 91.2
| ASW | 1.8 | 12.3 | 86.0
| CHB | 5.8 | 35.8 | 58.4
| CHD | 9.2 | 31.2 | 59.6
| GIH | 1.0 | 17.8 | 81.2
| LWK | 0.9 | 19.1 | 80.0
| MEX | 1.7 | 24.1 | 74.1
| MKK | 0.0 | 8.3 | 91.7
| TSI | 2.9 | 26.5 | 70.6
| HapMapRevision=28
}}{{PMID Auto
|PMID=20032318
|Title=Variants of DENND1B associated with asthma in children
}}

{{PharmGKB
|RSID=rs2786098
|Name_s=
|Gene_s=MRPS21P3, CRB1
|Feature=
|Evidence=PubMed ID:20032318
|Annotation=Risk or phenotype-associated allele: A. Phenotype: This variant is associated with asthma in children of European ancestry. Study size: Initial sample:793 European ancestry child cases, 1,988 European ancestry child controls; Replication Sample: 917 European ancestry child cases, 1,546 European ancestry child controls, 1,667 African American child cases, 2,045 African American child controls. Study population/ethnicity: European; african american. Significance metric(s): P=1.6x10-13 for the comparison across all samples. Type of association: GN; CO
|Drugs=
|Drug Classes=
|Diseases=Asthma
|Curation Level=Curated
|PharmGKB Accession ID=PA165111766
}}

{{omim
|id=600807
|rsnum=2786098
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2786098
|overall_frequency_n=103
|overall_frequency_d=128
|overall_frequency=0.804688
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=88
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23028483
|Title=Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}