{{Rsnum
|rsid=279836
|Gene=GABRA2
|Chromosome=4
|position=46337053
|Orientation=plus
|GMAF=0.4224
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=GABRA2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 22.2 | 54.0 | 23.8
| HCB | 27.9 | 58.1 | 14.0
| JPT | 22.0 | 46.3 | 31.7
| YRI | 1.7 | 28.3 | 70.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 27.9 | 58.1 | 14.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

This SNP in the [[GABRA2]] gene has been linked to [[Alcoholism]].

The strongest association for this SNP is seen when it is a member of a haplotype consisting of the [[rs279871]](A) + [[rs279845]](T) + [[rs279836]](A) alleles {{PMID|15024690|OA=1
}}.

{{omim
|id=137140
|desc=GAMMA-AMINOBUTYRIC ACID RECEPTOR, ALPHA-2; GABRA2
|rsnum=279836
}}

{{omim
|id=137140
|rsnum=279836
|variant=0003
}}

{{PMID Auto
|PMID=22501025
|Title=GABRA2 markers moderate the subjective effects of alcohol
|OA=1
}}

{{PMID Auto
|PMID=18634760
|Title=Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes.
|OA=1
}}

{{PMID Auto
|PMID=18727688
|Title=The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample.
|OA=1
}}

{{PMID Auto
|PMID=19487630
|Title=Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring.
|OA=1
}}

{{PMID Auto
|PMID=20133874
|Title=Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}