{{Rsnum
|rsid=280519
|Gene=TYK2
|Chromosome=19
|position=10362257
|Orientation=plus
|GMAF=0.4743
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=TYK2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 23.0 | 51.3 | 25.7
| HCB | 16.4 | 54.5 | 29.1
| JPT | 30.6 | 45.9 | 23.4
| YRI | 21.4 | 42.1 | 36.6
| ASW | 14.3 | 48.2 | 37.5
| CHB | 16.4 | 54.5 | 29.1
| CHD | 20.2 | 45.0 | 34.9
| GIH | 22.0 | 49.0 | 29.0
| LWK | 11.8 | 50.9 | 37.3
| MEX | 39.7 | 50.0 | 10.3
| MKK | 9.6 | 43.6 | 46.8
| TSI | 37.3 | 36.3 | 26.5
| HapMapRevision=28
}}{{PMID Auto
|PMID=19440814
|Title=Lack of association between tyrosine kinase 2 (TYK2) gene polymorphisms and susceptibility to SLE in a Japanese population
}}; No association was seen between this SNP and SLE in a study of 411 Japanese SLE patients.

{{PMID Auto
|PMID=19653082
|Title=Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn's Disease in the Japanese Population
|OA=1
}}

{{PMID Auto GWAS
|PMID=20953190
|Trait=None
|Title=A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
|RiskAllele=A
|Pval=4E-9
|OR=1.1300
|ORtxt=[1.05-1.21]
|OA=1
}}

{{PMID Auto
|PMID=21140222
|Title=Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases
}}

{{PMID Auto
|PMID=15657875
|Title=Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=19838195
|Title=A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=22592861
|Title=Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}