{{Rsnum
|rsid=2816316
|Chromosome=1
|position=192567683
|Orientation=minus
|GMAF=0.2227
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 5.3 | 29.2 | 65.5
| HCB | 3.6 | 25.5 | 70.8
| JPT | 7.1 | 44.2 | 48.7
| YRI | 7.5 | 39.5 | 53.1
| ASW | 3.5 | 40.4 | 56.1
| CHB | 3.6 | 25.5 | 70.8
| CHD | 4.6 | 22.0 | 73.4
| GIH | 0.0 | 11.9 | 88.1
| LWK | 5.5 | 31.2 | 63.3
| MEX | 10.3 | 37.9 | 51.7
| MKK | 8.3 | 34.0 | 57.7
| TSI | 3.9 | 26.5 | 69.6
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs2816316
|PubMedID=18311140
|Condition=Celiac disease
|Gene=RGS1
|Risk Allele=C
|pValue=3.00E-011
|OR=1.39
|95CI=1.26-1.53
|OA=1
}}

{{omim
|desc=CELIAC DISEASE; CD
|id=212750
|rsnum=2816316
}}

{{omim
|desc=CELIAC DISEASE, SUSCEPTIBILITY TO, 7; CELIAC7
|id=612005
|rsnum=2816316
}}
{{PMID Auto
|PMID=19693089
|Title=Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort
}}

{{PharmGKB
|RSID=rs2816316
|Name_s=
|Gene_s=RGS1
|Feature=
|Evidence=PubMed ID:18311140; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Newly identified genetic risk variants for celiac disease related to the immune response (Initial Sample Size: 767 cases, 1,422 controls; Replication Sample Size: 1,643 cases, 3,406 controls; Risk Allele: rs2816316-C).
|Drugs=
|Drug Classes=
|Diseases=Celiac Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356756
}}

{{PMID Auto GWAS
|PMID=20190752
|Trait=Celiac disease
|Title=Multiple common variants for celiac disease influencing immune gene expression
|RiskAllele=
|Pval=2E-17
|OR=1.25
|ORtxt=[1.19-1.32]
|OA=1
}}

{{PMID Auto
|PMID=22087237
|Title=Improving the estimation of celiac disease sibling risk by non-HLA genes
|OA=1
}}

{{PMID|18713140|OA=1
}} Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.

{{PMID|18853133|OA=1
}} Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

{{PMID|19073967|OA=1
}} Shared and distinct genetic variants in type 1 diabetes and celiac disease.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2816316
|overall_frequency_n=86
|overall_frequency_d=106
|overall_frequency=0.811321
|n_genomes=42
|n_genomes_annotated=0
|n_haplomes=75
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}