{{Rsnum
|rsid=2819770
|Gene=RYR2
|Chromosome=1
|position=237747704
|Orientation=minus
|GMAF=0.1524
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=RYR2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 7.1 | 39.8 | 53.1
| HCB | 0.7 | 7.3 | 92.0
| JPT | 0.0 | 7.1 | 92.9
| YRI | 0.0 | 10.2 | 89.8
| ASW | 0.0 | 24.6 | 75.4
| CHB | 0.7 | 7.3 | 92.0
| CHD | 0.0 | 11.9 | 88.1
| GIH | 3.0 | 26.7 | 70.3
| LWK | 0.0 | 4.6 | 95.4
| MEX | 10.3 | 36.2 | 53.4
| MKK | 0.6 | 21.2 | 78.2
| TSI | 6.9 | 39.2 | 53.9
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs2819770
|PubMedID=17903301
|Condition=Exercise treadmill test traits
|Gene=RYR2
|Risk Allele=
|pValue=4.00E-006
|OR=NA
|95CI=
|OA=1
}}

{{PharmGKB
|RSID=rs2819770
|Name_s=
|Gene_s=RYR2
|Feature=
|Evidence=PubMed ID:17903301; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study (Initial Sample Size: 1,238 individuals (Framingham); Replication Sample Size: NR). This variant is associated with Exercise treadmill test traits.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356471
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2819770
|overall_frequency_n=23
|overall_frequency_d=126
|overall_frequency=0.18254
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}