{{Rsnum
|rsid=2822432
|Gene=LIPI
|Chromosome=21
|position=14144627
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.3186
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LIPI
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 44.4 | 39.7 | 15.9
| HCB | 91.1 | 8.9 | 0.0
| JPT | 79.5 | 18.2 | 2.3
| YRI | 18.9 | 46.2 | 35.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 91.1 | 8.9 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 51.0 | 41.8 | 7.1
| LWK | 17.9 | 54.7 | 27.4
| MEX | 0.0 | 0.0 | 0.0
| MKK | 29.1 | 46.4 | 24.5
| TSI | 39.2 | 52.6 | 8.2
| HapMapRevision=28
}}

{{Venter SNP
|rsid=2822432
|allele=T
|frequency=
|uid=1103643073626
|type=homozygous_SNP
|hugo=LIPI
|ensembl gene=ENSG00000188992
|ensembl transcript=ENST00000344577
|sift=AFFECT FUNCTION
|disease=Defects in LIPI may be a cause of susceptibility to familial hypertrigliceridemia (MIM:145750). Familial hypertriglyceridemia is a common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma. This leads to increased risk of heart disease, obesity, and pancreatitis.
}}

{{ neighbor
| rsid = 7283442
| distance = 28
}}

{{GET Evidence
|gene=LIPI
|aa_change=Glu452Lys
|aa_change_short=E452K
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2822432
|overall_frequency_n=4341
|overall_frequency_d=10746
|overall_frequency=0.403964
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=37
|n_articles=0
|n_articles_annotated=0
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}