{{Rsnum
|rsid=2836823
|Gene=TMPRSS11E
|Chromosome=21
|position=39008323
|Orientation=plus
|GMAF=0.2521
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LOC102724740
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 29.2 | 46.0 | 24.8
| HCB | 94.9 | 4.4 | 0.7
| JPT | 89.4 | 10.6 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 87.7 | 10.5 | 1.8
| CHB | 94.9 | 4.4 | 0.7
| CHD | 91.7 | 8.3 | 0.0
| GIH | 76.2 | 19.8 | 4.0
| LWK | 99.1 | 0.9 | 0.0
| MEX | 27.6 | 55.2 | 17.2
| MKK | 94.9 | 5.1 | 0.0
| TSI | 32.4 | 46.1 | 21.6
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs2836823
|PubMedID=17158188
|Condition=Nicotine dependence
|Gene=NR
|Risk Allele=T
|pValue=2.00E-006
|OR=1.46
|95CI=1.23-1.73
|OA=1
}}

{{PharmGKB
|RSID=rs2836823
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17158188; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Novel genes identified in a high-density genome wide association study for nicotine dependence (Initial Sample Size: 1,050 cases, 879 controls; Replication Sample Size: NR; Risk Allele: rs2836823-T).
|Drugs=nicotine
|Drug Classes=
|Diseases=Tobacco Use Disorder
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356597
}}

{{PMID Auto
|PMID=18565990
|Title=Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.
|OA=1
}}

{{PMID Auto
|PMID=19184766
|Title=A testable prognostic model of nicotine dependence.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2836823
|overall_frequency_n=28
|overall_frequency_d=128
|overall_frequency=0.21875
|n_genomes=16
|n_genomes_annotated=0
|n_haplomes=19
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}