{{Rsnum
|rsid=2844682
|Chromosome=6
|position=30978371
|Orientation=minus
|GMAF=0.1515
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 78.8 | 21.2 | 0.0
| HCB | 78.1 | 21.2 | 0.7
| JPT | 66.4 | 31.9 | 1.8
| YRI | 76.9 | 19.7 | 3.4
| ASW | 70.2 | 29.8 | 0.0
| CHB | 78.1 | 21.2 | 0.7
| CHD | 82.6 | 15.6 | 1.8
| GIH | 87.1 | 11.9 | 1.0
| LWK | 80.0 | 17.3 | 2.7
| MEX | 58.6 | 36.2 | 5.2
| MKK | 87.8 | 12.2 | 0.0
| TSI | 67.6 | 31.4 | 1.0
| HapMapRevision=28
}}

Helps to identify [[HLA-B*1502]]

{{PharmGKB
|RSID=rs2844682
|Name_s=
|Gene_s=MUC21
|Feature=
|Evidence=PubMed ID:16998491
|Annotation=Risk or phenotype-associated allele: allele 4. Phenotype: Combined alleles of rs3909184 (2) and rs2844682 (4) are tagging SNPs for HLA-B*1502 (0.011 allele frequency). Study size: 45. Study population/ethnicity: Unrelated Han Chinese from Beijing, China. Significance metric(s): Type of association: GN
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165291971
}}

{{PharmGKB
|RSID=rs2844682
|Name_s=tagging SNP for HLA-B*1502
|Gene_s=MUC21
|Feature=
|Evidence=PubMed ID:15057820; PubMed ID:16415921; PubMed ID:16538176; PubMed ID:16998491; PubMed ID:18370849; PubMed ID:18637831; Web Resource:http://www.fda.gov/cder/drug/InfoSheets/HCP/carbamazepineHCP.htm
|Annotation=This variant is a tagging SNP for HLA-B*1502, which is associated with severe adverse reactions of carbamazepine. Patients carrying the HLA-B*1502 allele have significant higher risk for severe skin reactions (Stevens Johnson syndrome and toxic epidermal necrolysis) associated with carbamazepine therapy.
|Drugs=carbamazepine; phenytoin
|Drug Classes=
|Diseases=Bipolar Disorder; Epidermal Necrolysis, Toxic; Epilepsy; Stevens-Johnson Syndrome
|Curation Level=Curated
|PharmGKB Accession ID=PA162168984
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2844682
|overall_frequency_n=21
|overall_frequency_d=128
|overall_frequency=0.164062
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=18
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}