{{Rsnum
|rsid=2854128
|Gene=MT-RNR2
|Chromosome=MT
|position=2706
|Orientation=plus
|GMAF=0.1656
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=132
|Summary=G2706A, defines MT-Haplogroup H
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 45.3 | 1.6 | 53.1
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
{{hgsnp
|alternate_names=G2706A
|sources={{PMID|17099056}},{{PMID|15382008|OA=1
}},{{PMID|15254257}},Palanichamy 2004
|tree=PhyloTree
|tree_build=7
|ancestral_haplogroup=HV
|derived_haplogroup=H
|ancestral_allele=G
|derived_allele=A
}}
More commonly known as G2706A, this is one of the two ancestral mitochondrial mutations that define [[Mitochondrial Haplogroup]] H. However, this is also a mutation which changes both the RNA of the mitochondrial ribosome (potentially changing its shape and function) and the protective protein humanin which is encoded from the RNA of the ribosome itself.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}