{{Rsnum
|rsid=2854344
|Gene=RB1
|Chromosome=13
|position=48423557
|Orientation=plus
|GMAF=0.02204
|Gene_s=LPAR6,RB1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 11.5 | 87.6
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 3.0 | 97.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 1.7 | 98.3
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 3.0 | 97.0
| HapMapRevision=28
}}associated with [[breast cancer]] risk {{PMID|16685266|OA=1
}} and [[ovarian cancer]] {{PMID|17047088}}

More specifically: carriers of two [[rs2854344]](A) alleles have a 25% reduced risk of developing ovarian cancer compared to carriers of two [[rs2854344]](G) alleles, in a survey of ~5,000 women from the US, UK, and Denmark. {{PMID|17047088}}

{{PMID|18431743|OA=1
}}  showed '''no association''' with ovarian cancer risk 4,624 invasive epithelial ovarian cancer cases and 8,113 controls of white non-Hispanic origin [[ovarian cancer]]

{{PMID Auto
|PMID=18174243
|Title=Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.
|OA=1
}}

{{PMID Auto
|PMID=18281541
|Title=Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.
|OA=1
}}

{{PMID Auto
|PMID=19124506
|Title=Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
|OA=1
}}

{{PMID Auto
|PMID=19258477
|Title=Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=21641967
|Title=Genetic susceptibility to sporadic ovarian cancer: A systematic review.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}