{{Rsnum
|rsid=2854744
|Gene=IGFBP3
|Chromosome=7
|position=45921476
|Orientation=minus
|GMAF=0.4513
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=IGFBP3
}}{{PMID Auto
|PMID=19240240
|Title=IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women
|OA=1
}}

{{PMID Auto
|PMID=19455605
|Title=Genetic and plasma variation of insulin-like growth factor binding proteins in relation to prostate cancer incidence and survival
}}

{{PMID Auto
|PMID=19551864
|Title=Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease
|OA=1
}}

{{omim
|desc=INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3; IGFBP3
|id=146732
|rsnum=2854744
}}
{{PMID Auto
|PMID=19784788
|Title=Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk
}}
{{PMID Auto
|PMID=19786971
|Title=Associations of insulin-like growth factor binding protein-3 gene polymorphisms with IGF-I activity and lipid parameters in adolescents
}}
{{PMID Auto
|PMID=19858071
|Title=Common Genetic Variation in IGF1, IGFBP1, and IGFBP3 and Ovarian Cancer Risk
|OA=1
}}

{{PMID Auto
|PMID=20484221
|Title=A Comprehensive Analysis of Common IGF1, IGFBP1 and IGFBP3 Genetic Variation with Prospective IGF-I and IGFBP-3 Blood Levels and Prostate Cancer Risk Among Caucasians
|OA=1
}}
{{PMID Auto
|PMID=21140206
|Title=IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families
}}

{{PMID Auto
|PMID=21347663
|Title=The association between bladder cancer and a single nucleotide polymorphism (rs2854744) in the insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) gene
}}

{{PMID Auto
|PMID=21892705
|Title=Urinary bladder cancer risk in relation to a single nucleotide polymorphism (rs2854744) in the insulin-like growth factor-binding protein-3 (IGFBP3) gene
}}

{{PMID Auto
|PMID=21552154
|Title=Common genetic variation in the IGF1 associates with maximal force output
}}

{{PMID Auto
|PMID=18769619
|Title=Vocal communication and reproduction in deer.
|OA=1
}}

{{PMID Auto
|PMID=22253814
|Title=A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme
|OA=1
}}

{{PMID|15113441|OA=1
}} Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes.

{{PMID|16306136}} IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.

{{PMID|17063263}} Genetic variation in IGF1, IGF-1R, IGFALS, and IGFBP3 in breast cancer survival among Chinese women: a report from the Shanghai Breast Cancer Study.

{{PMID|17293864}} A common coding variant in CASP8 is associated with breast cancer risk.

{{PMID|17300730|OA=1
}} Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.

{{PMID|17566087}} Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein (BP)-1, and IGFBP-3 levels in a multiethnic population.

{{PMID|18031946}} Polymorphisms in the insulin like growth factor 1 and IGF binding protein 3 genes and risk of colorectal cancer.

{{PMID|18398029}} Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels.

{{PMID|18398040|OA=1
}} Transcription factor 7-like 2 polymorphism and colon cancer.

{{PMID|18596909|OA=1
}} IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

{{PMID|18984657}} The -202 A allele of insulin-like growth factor binding protein-3 (IGFBP3) promoter polymorphism is associated with higher IGFBP-3 serum levels and better growth response to growth hormone treatment in patients with severe growth hormone deficiency.

{{PMID|18992148|OA=1
}} Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

{{PMID|18992263|OA=1
}} Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

{{PMID|19077426|OA=1
}} On combining triads and unrelated subjects data in candidate gene studies: an application to data on testicular cancer.

{{PMID|19551141|OA=1
}} Analysis of germline variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in familial and sporadic renal cell carcinoma.

{{PMID|19634593|OA=1
}} Predictors of variation in serum IGF1 and IGFBP3 levels in healthy African American and white men.

{{PMID|19938081|OA=1
}} Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.

{{PMID|20302654|OA=1
}} Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.

{{PMID|21314884}} Insulin-like growth factor binding protein-3 (IGFBP-3) gene variants are associated with renal cell carcinoma.

{{PMID|22354904}} Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study.

{{PMID|22565227}} Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites.

{{PMID Auto
|PMID=23174226
|Title=The Influence of Promoter -202 A/C Polymorphism (rs2854744) of the IGFBP-3 Gene on Erectile Dysfunction Risk and Serum Levels of IGF-I and IGFBP-3
}}

{{PMID Auto
|PMID=24905066
|Title=GENETIC PREDICTORS OF LONG-TERM RESPONSE TO GROWTH HORMONE (GH) THERAPY IN CHILDREN WITH GH DEFICIENCY AND TURNER SYNDROME: THE INFLUENCE OF A SOCS2 POLYMORPHISM
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}