{{Rsnum
|rsid=28928904
|Gene=KCNH2
|Orientation=minus
|ReferenceAllele=T
|MissenseAllele=G
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Chromosome=7
|position=150951615
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=KCNH2
}}influences the [[QT interval]]
{{omim
|desc=LONG QT SYNDROME 2
|id=152427
|rsnum=28928904
|variant=0004
}}
{{ neighbor
| rsid = 28928905
| distance = 899
}}

{{ClinVar
|rsid=28928904
|Reversed=1
|FwdREF=T
|FwdALT=A,C,G
|REF=A
|ALT=C,G,T
|RSPOS=150648703
|CHROM=7
|dbSNPBuildID=133
|SSR=0
|SAO=1
|VP=0x050168000000000002110104
|GENEINFO=KCNH2:3757
|GENE_NAME=KCNH2
|GENE_ID=3757
|WGT=0
|VC=SNV
|CLNALLE=1; 2; 3
|CLNHGVS=NC_000007.13:g.150648703A>C; NC_000007.13:g.150648703A>G; NC_000007.13:g.150648703A>T
|CLNORIGIN=1
|CLNSRCID=
152427.0004
|CLNSIG=5
|CLNCUI=
|CLNACC=
RCV000015504.24; RCV000057986.1; RCV000057985.1; RCV000057984.1
|Tags=RV;PM;PMC;SLO;OTHERKG;LSD;OM;NOV
|CLNDBN=Long QT syndrome 2; not provided
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet
|CLNDSDBID=NBK1129:C3150943:613688:101016
|CLNSRC=OMIM Allelic Variant
|Disease=Long QT syndrome 2; not provided
}}

{{PMID Auto
|PMID=19214780
|Title=In silico investigations on functional and haplotype tag SNPs associated with congenital long QT syndromes (LQTSs).
|OA=1
}}

{{PMID Auto
|PMID=8635257
|Title=Missense mutation in the pore region of HERG causes familial long QT syndrome.
}}

{{PMID Auto
|PMID=10973849
|Title=Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2.
}}

{{PMID Auto
|PMID=16432067
|Title=Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
}}

{{PMID Auto
|PMID=16922724
|Title=Spectrum of pathogenic mutations and associated polymorphisms in a cohort of 44 unrelated patients with long QT syndrome.
}}

{{PMID Auto
|PMID=19716085
|Title=Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}