{{Rsnum
|rsid = 28931569
|Gene = SERPINA1
|Orientation=minus
|ReferenceAllele=T
|MissenseAllele=C
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Chromosome=14
|position=94383044
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=SERPINA1
}}[[rs28931569]] is a SNP representing an amino acid change in the [[SERPINA1]] gene, which encodes alpha-1-antitrypsin (AAT).

Carriers of two [[rs28931569]](C) alleles, i.e. homozygotes, are at high risk for [[emphysema]] .{{PMID|269618}}

{{omim
|desc=PI M(PROCIDA)
|id=107400
|rsnum=28931569
|variant=0016
}}
{{ neighbor
| rsid = 28931568
| distance = 78
}}
{{ neighbor
| rsid = 28931570
| distance = 7
}}

{{ClinVar
|rsid=28931569
|Reversed=1
|FwdREF=T
|FwdALT=C
|REF=A
|ALT=G
|RSPOS=94849381
|CHROM=14
|dbSNPBuildID=136
|SSR=0
|SAO=1
|VP=0x050268000000000002110100
|GENEINFO=SERPINA1:5265
|GENE_NAME=SERPINA1
|GENE_ID=5265
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000014.8:g.94849381A>G
|CLNORIGIN=0
|CLNSIG=255
|Tags=RV;PM;PMC;S3D;OTHERKG;LSD;OM
|CLNACC=RCV000019571.1
|CLNDBN=PI M(PROCIDA)
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=107400.0016
|Disease=PI M(PROCIDA)
}}

{{PMID Auto
|PMID=3262617
|Title=Characterization of the gene and protein of the alpha 1-antitrypsin "deficiency" allele Mprocida.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}