{{Rsnum
|rsid=2941740
|Gene=ESR1
|Chromosome=6
|position=151688503
|Orientation=minus
|GMAF=0.337
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ESR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 22.6 | 40.3 | 37.1
| HCB | 0.0 | 20.0 | 80.0
| JPT | 6.8 | 38.6 | 54.5
| YRI | 8.1 | 50.0 | 41.9
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 20.0 | 80.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19801982
|Trait=Bone mineral density (hip)
|Title=Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
|RiskAllele=G
|Pval=2E-10
|OR=0.07
|ORtxt=[0.05-0.09] sd increase
|OA=1
}}

{{PMID Auto
|PMID=23072920
|Title=Genetic markers of bone and joint health and physical capability in older adults: the HALCyon programme
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2941740
|overall_frequency_n=45
|overall_frequency_d=128
|overall_frequency=0.351562
|n_genomes=34
|n_genomes_annotated=0
|n_haplomes=40
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}