{{Rsnum
|rsid=2943650
|Chromosome=2
|position=226241205
|Orientation=plus
|GMAF=0.3329
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 23.0 | 37.7 | 39.3
| HCB | 0.0 | 20.0 | 80.0
| JPT | 0.0 | 13.6 | 86.4
| YRI | 41.3 | 46.0 | 12.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 20.0 | 80.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=21706003
|Trait=None
|Title=Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
|RiskAllele=T
|Pval=4E-11
|OR=0.0300
|ORtxt=[NR] % decrease
|OA=1
}}
{{PMID Auto
|PMID=23659870
|Title=Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study
}}{{PMID Auto
|PMID=22797928
|Title=Evidence of selection at insulin receptor substrate-1 gene loci.
}}

{{PMID Auto
|PMID=23708086
|Title=NUDT3 rs206936 is associated with body mass index in obese Japanese women.
}}