{{Rsnum
|rsid=2960306
|Gene=GRK4
|Chromosome=4
|position=2988772
|Orientation=plus
|GMAF=0.3365
|Gene_s=GRK4
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 39.8 | 46.0 | 14.2
| HCB | 80.9 | 18.4 | 0.7
| JPT | 79.6 | 20.4 | 0.0
| YRI | 21.2 | 45.9 | 32.9
| ASW | 26.8 | 39.3 | 33.9
| CHB | 80.9 | 18.4 | 0.7
| CHD | 88.1 | 11.0 | 0.9
| GIH | 74.3 | 25.7 | 0.0
| LWK | 19.1 | 49.1 | 31.8
| MEX | 39.7 | 48.3 | 12.1
| MKK | 31.4 | 55.1 | 13.5
| TSI | 39.2 | 48.0 | 12.7
| HapMapRevision=28
}}{{PMID Auto
|PMID=22639547
|Title=Pooled Analyses of the Associations of Polymorphisms in the GRK4 and EMILIN1 Genes with Hypertension Risk
|OA=1
}}

{{PMID|19119263|OA=1
}} G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions.

{{GET Evidence
|gene=GRK4
|aa_change=Arg65Leu
|aa_change_short=R65L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2960306
|overall_frequency_n=4314
|overall_frequency_d=10758
|overall_frequency=0.401004
|n_genomes=36
|n_genomes_annotated=0
|n_haplomes=44
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.019
|nblosum100=6
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23133444
|Title=Genetic variation in CYP17A1 is associated with arterial stiffness in diabetic subjects
|OA=1
}}

{{PMID Auto
|PMID=22949529
|Title=G protein receptor kinase 4 polymorphisms: beta-blocker pharmacogenetics and treatment-related outcomes in hypertension.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}