{{Rsnum
|rsid=2976392
|Gene=PSCA
|Chromosome=8
|position=142681514
|Orientation=plus
|GMAF=0.4311
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PSCA
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 16.8 | 50.4 | 32.7
| HCB | 6.6 | 45.3 | 48.2
| JPT | 32.7 | 53.1 | 14.2
| YRI | 6.8 | 34.9 | 58.2
| ASW | 19.3 | 54.4 | 26.3
| CHB | 6.6 | 45.3 | 48.2
| CHD | 8.3 | 46.8 | 45.0
| GIH | 22.8 | 53.5 | 23.8
| LWK | 17.3 | 50.9 | 31.8
| MEX | 31.0 | 50.0 | 19.0
| MKK | 30.1 | 39.1 | 30.8
| TSI | 14.7 | 52.9 | 32.4
| HapMapRevision=28
}}{{PMID|18488030}} [[rs2976392]] and diffuse-type [[gastric cancer]] (allele-specific odds ratio (OR) = 1.62, 95% CI = 1.38-1.89, P = 1.11 x 10(-9)). Substitution of the C allele with the risk allele T at a SNP in the first exon ([[rs2294008]], which has r(2) = 0.995, D' = 0.999 with rs2976392) reduces transcriptional activity of an upstream fragment of the gene

{{omim
|desc=GASTRIC CANCER
|id=137215
|rsnum=2976392
}}

{{omim
|desc=PROSTATE STEM CELL ANTIGEN; PSCA
|id=602470
|rsnum=2976392
}}

{{PMID Auto
|PMID=20131315
|Title=Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-gastric cancer in a Chinese population
}}

{{PMID Auto
|PMID=22481254
|Title=The PSCA polymorphisms derived from genome-wide association study are associated with risk of gastric cancer: a meta-analysis
}}

{{PMID Auto
|PMID=19554573
|Title=Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population.
}}

{{PMID Auto
|PMID=19582881
|Title=Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese.
}}

{{PMID Auto
|PMID=22037551
|Title=A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.
}}

{{PMID Auto
|PMID=22426141
|Title=Prostate stem cell antigen polymorphisms and susceptibility to gastric cancer: a systematic review and meta-analysis.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}