{{Rsnum
|rsid=2977838
|Gene=SLC39A4
|Chromosome=8
|position=144415027
|Orientation=minus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.03535
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=SLC39A4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 88.5 | 11.5 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=2977838
|allele=G
|frequency=0.938
|uid=1103652472439
|type=homozygous_SNP
|hugo=SLC39A4
|ensembl gene=ENSG00000147804
|ensembl transcript=ENST00000301305
|sift=TOLERATED
|disease=Defects in SLC39A4 are the cause of acrodermatitis enteropathica zinc-deficiency type (AEZ) (MIM:201100). AEZ is a rare autosomal recessive disease caused by the inability to absorb sufficient zinc. The clinicals features are growth retardation, immune-system dysfunction, alopecia, severe dermatitis, diarrhea and occasionally mental disorders.
}}

{{ neighbor
| rsid = 17855765
| distance = 917
}}

{{GET Evidence
|gene=SLC39A4
|aa_change=Trp251Arg
|aa_change_short=W251R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2977838
|overall_frequency_n=10404
|overall_frequency_d=10756
|overall_frequency=0.967274
|n_genomes=42
|n_genomes_annotated=0
|n_haplomes=83
|n_articles=0
|n_articles_annotated=0
|nblosum100=7
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}