{{Rsnum
|rsid=29941
|Chromosome=19
|position=33818627
|Orientation=minus
|GMAF=0.3972
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 48.6 | 38.7 | 12.6
| HCB | 8.0 | 38.7 | 53.3
| JPT | 8.0 | 35.4 | 56.6
| YRI | 72.8 | 26.5 | 0.7
| ASW | 75.0 | 23.2 | 1.8
| CHB | 8.0 | 38.7 | 53.3
| CHD | 4.6 | 39.4 | 56.0
| GIH | 48.5 | 40.6 | 10.9
| LWK | 78.2 | 20.9 | 0.9
| MEX | 37.9 | 53.4 | 8.6
| MKK | 60.7 | 32.0 | 7.3
| TSI | 45.1 | 47.1 | 7.8
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19079260
|Trait=Body mass index
|Title=Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
|RiskAllele=C
|Pval=7E-12
|OR=4.18
|ORtxt=[2.98-5.38] % SD
}}

{{PharmGKB
|RSID=rs29941
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19079260; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (Initial Sample Size: 80,969 individuals; Replication Sample Size: 11,036 individuals); (Region: 19q13.11; Reported Gene(s): KCTD15, CHST8; Risk Allele: rs29941-C); (p-value= 0.000000005).This variant is associated with Weight.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740167
}}

{{PMID Auto
|PMID=20061430
|Title=Obesity Susceptibility Genetic Variants Identified from Recent Genome-Wide Association Studies: Implications in a Chinese Population
}}

{{PharmGKB
|RSID=rs29941
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19079260; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (Initial Sample Size: 80,969 individuals; Replication Sample Size: 11,036 individuals); (Region: 19q13.11; Reported Gene(s): KCTD15, CHST8; Risk Allele: rs29941-C); (p-value= 0.000000000007).This variant is associated with Body mass index.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740145
}}
{{PMID Auto GWAS
|PMID=20935630
|Trait=None
|Title=Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
|RiskAllele=G
|Pval=3E-9
|OR=0.06
|ORtxt=[0.02-0.10] kg/m2 increase
|OA=1
}}

{{PMID Auto
|PMID=21796141
|Title=Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area
}}

{{PMID Auto
|PMID=21912638
|Title=Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
|OA=1
}}

{{PMID Auto
|PMID=22355368
|Title=Longitudinal Replication Studies of GWAS Risk SNPs Influencing Body Mass Index over the Course of Childhood and Adulthood
|OA=1
}}

{{PMID Auto
|PMID=19478790
|Title=The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
|OA=1
}}

{{PMID Auto
|PMID=19553259
|Title=Common body mass index-associated variants confer risk of extreme obesity.
|OA=1
}}

{{PMID Auto
|PMID=20127379
|Title=From monogenic to polygenic obesity: recent advances.
|OA=1
}}

{{PMID Auto
|PMID=20712903
|Title=Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
|OA=1
}}

{{PMID Auto
|PMID=22179955
|Title=Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.
|OA=1
}}

{{PMID Auto
|PMID=22511254
|Title=Susceptibility variants for obesity and colorectal cancer risk: The multiethnic cohort and PAGE studies.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs29941
|overall_frequency_n=92
|overall_frequency_d=128
|overall_frequency=0.71875
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=77
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23424664
|Title=Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children
|OA=1
}}

{{PMID Auto
|PMID=24269186
|Title=An obesity genetic risk score is associated with metabolic syndrome in Chinese children
}}

{{PMID Auto
|PMID=23121087
|Title=Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}