{{Rsnum
|rsid=3018362
|Gene=RPL17P44
|Chromosome=18
|position=62414860
|Orientation=plus
|GMAF=0.416
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 10.7 | 52.7 | 36.6
| HCB | 50.7 | 40.3 | 9.0
| JPT | 48.7 | 38.9 | 12.4
| YRI | 4.8 | 27.9 | 67.3
| ASW | 7.0 | 24.6 | 68.4
| CHB | 50.7 | 40.3 | 9.0
| CHD | 42.2 | 48.6 | 9.2
| GIH | 11.9 | 49.5 | 38.6
| LWK | 1.8 | 26.4 | 71.8
| MEX | 17.2 | 53.4 | 29.3
| MKK | 3.2 | 14.7 | 82.1
| TSI | 5.9 | 45.1 | 49.0
| HapMapRevision=28
}}
rs3018362 increases susceptibility to Osteoporotic fractures for carriers of the A allele {{PMID|18445777}}

related to  [[Paget’s disease of bone]] [http://blog.23andme.com/2010/05/19/snpwatch-genetic-variants-associated-with-risk-of-pagets-disease-of-bone-identified/ 23andMe blog]. 

{{PMID Auto GWAS
|PMID=20436471
|Trait=Paget's disease
|Title=Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone
|RiskAllele=A
|Pval=5E-13
|OR=1.52
|ORtxt=[1.36-1.70]
|OA=1
}}

{{omim
|id=602080
|rsnum=3018362
}}

{{PMID Auto GWAS
|PMID=21623375
|Trait=None
|Title=Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.
|RiskAllele=A
|Pval=8E-21
|OR=1.4500
|ORtxt=[1.34-1.56]
}}

{{PMID Auto
|PMID=20072603
|Title=Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
|OA=1
}}

{{PMID Auto
|PMID=20534768
|Title=OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.
|OA=1
}}

{{PMID Auto
|PMID=20554715
|Title=Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3018362
|overall_frequency_n=90
|overall_frequency_d=128
|overall_frequency=0.703125
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=76
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23531404
|Title=Association of genetic polymorphisms of RANK, RANKL and OPG with bone mineral density in Chinese peri- and postmenopausal women.
}}

{{PMID Auto
|PMID=24921058
|Title=Receptor activator of nuclear factor kappa-B gene polymorphisms in Iranian periodontitis and peri-implantitis patients
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}