{{Rsnum
|rsid=3025786
|Gene=PSEN1
|Chromosome=14
|position=73198010
|Orientation=plus
|GMAF=0.02893
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=PSEN1
}}[[rs3025786]] is a SNP in the presenilin 1 [[PSEN1]] gene.

A study of a Spanish case-control sample of 1,183 individuals showed [[rs3025786]] was associated with [[Alzheimer's disease]] in an [[ApoE]]-specific manner: more specifically [[rs3025786]](C) allele carriers have a decreased AD risk among carriers of the [[ApoE4]] allele.
{{PMID|18957849}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}