{{Rsnum
|rsid=307377
|Gene=TAS1R3
|Chromosome=1
|position=1334174
|Orientation=plus
|GMAF=0.0404
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Summary=umami taste sensitivity
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TAS1R3
}}Influences [[taste|tasting]] ability. 

This [http://blogs.discovermagazine.com/gnxp/2009/07/genetics-of-taste-umami-polymorphisms-on-tas1r/ blog] entry discusses the research.

{{PMID|19587085|OA=1
}} the rare T allele of [[rs307377]](T) (R757C) in [[TAS1R3]] led to a doubling of umami ratings of 25 mmol MPG/L. Other suggestive SNPs of TAS1R3 include the A allele of A5T and the A allele of R247H, which both resulted in an approximate doubling of umami ratings of 200 mmol MPG/L

{{PMID Auto
|PMID=16782140
|Title=Diverse tastes: Genetics of sweet and bitter perception.
|OA=1
}}

{{PMID Auto
|PMID=19092995
|Title=Bitter taste receptors influence glucose homeostasis.
|OA=1
}}

{{PMID Auto
|PMID=19696921
|Title=Genetic and molecular basis of individual differences in human umami taste perception.
|OA=1
}}

{{GET Evidence
|gene=TAS1R3
|aa_change=Cys757Arg
|aa_change_short=C757R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs307377
|overall_frequency_n=124
|overall_frequency_d=126
|overall_frequency=0.984127
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=105
|n_articles=0
|n_articles_annotated=0
|nblosum100=8
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}