{{Rsnum
|rsid=3092856
|Gene=ATM
|Chromosome=11
|position=108289005
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.01974
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ATM
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 100.0 | 0.0 | 0.0
| HCB | 97.8 | 2.2 | 0.0
| JPT | 93.2 | 6.8 | 0.0
| YRI | 79.4 | 20.6 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 97.8 | 2.2 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

This SNP, a variant in the [[ATM]] gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for [[breast cancer]]. {{PMID|17341484}}

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for [[breast cancer]], refer to the SNPedia [[breast cancer]] entry.

For this particular SNP, the risk (minor) allele is (T).
{{ neighbor
| rsid = 1800058
| distance = 618
}}

{{PMID Auto
|PMID=20232390
|Title=Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia
}}

{{PMID Auto
|PMID=18638378
|Title=Analysis of variants in DNA damage signalling genes in bladder cancer.
|OA=1
}}

{{GET Evidence
|gene=ATM
|aa_change=His1380Tyr
|aa_change_short=H1380Y
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3092856
|overall_frequency_n=281
|overall_frequency_d=10756
|overall_frequency=0.026125
|n_genomes=5
|n_genomes_annotated=0
|n_haplomes=5
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=-1
|autoscore=3
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}