{{Rsnum
|rsid=3129878
|Gene=HLA-DRA
|Chromosome=6
|position=32440958
|Orientation=plus
|GMAF=0.3108
|Gene_s=HLA-DRA
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}[[rs3129878]] is a SNP in the HLA gene region. It has been associated with slightly (~30%) higher risk for azoospermia (lack of sperm) and thus [[male infertility]] in both Chinese and Japanese men.{{PMID|22541561|OA=1
}}{{PMID|23934009}}

{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 55.8 | 40.7 | 3.5
| HCB | 43.1 | 44.5 | 12.4
| JPT | 22.1 | 52.2 | 25.7
| YRI | 61.2 | 32.0 | 6.8
| ASW | 52.6 | 38.6 | 8.8
| CHB | 43.1 | 44.5 | 12.4
| CHD | 53.2 | 39.4 | 7.3
| GIH | 56.4 | 34.7 | 8.9
| LWK | 50.5 | 31.2 | 18.3
| MEX | 48.3 | 37.9 | 13.8
| MKK | 36.5 | 51.3 | 12.2
| TSI | 57.8 | 34.3 | 7.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=23934009
|Title=HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients
}}

{{PMID Auto
|PMID=19846760
|Title=Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.
|OA=1
}}

{{PMID Auto
|PMID=22541561
|Title=A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}