{{Rsnum
|rsid=3132293
|Gene=RXRA
|Chromosome=9
|position=134433976
|Orientation=minus
|GMAF=0.1882
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=RXRA
}}A screen of SNPs in the [[RXRA]] gene in 405 [[Alzheimer's disease]] patients (mean age 74 +/- 9 years) suggests that the [[rs3132293]](G) allele (in dbSNP orientation) is associated with lower risk for the disease.{{PMID|18544046}}

However, it should be noted that (1) this allele is quite common, (2) there was a significant difference in the % of females (79%) in the patient population compared to the control population (57%), and (3) the magnitude of associated changes in cerebral cholesterol is not high.

{{PMID Auto
|PMID=19374686
|Title=RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism
}}

{{on chip | HumanOmni1Quad}}