{{Rsnum
|rsid=314277
|Gene=LIN28B
|Chromosome=6
|position=104959787
|Orientation=plus
|GMAF=0.197
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=LIN28B
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 0.9 | 24.1 | 75.0
| HCB | 0.0 | 5.1 | 94.9
| JPT | 0.9 | 14.2 | 85.0
| YRI | 17.7 | 51.0 | 31.3
| ASW | 17.5 | 50.9 | 31.6
| CHB | 0.0 | 5.1 | 94.9
| CHD | 0.9 | 10.1 | 89.0
| GIH | 3.0 | 30.7 | 66.3
| LWK | 20.9 | 61.8 | 17.3
| MEX | 0.0 | 17.2 | 82.8
| MKK | 18.7 | 43.9 | 37.4
| TSI | 3.9 | 28.4 | 67.6
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18391950
|Trait=Height
|Title=Identification of ten loci associated with height highlights new biological pathways in human growth
|RiskAllele=A
|Pval=1E-8
|OR=0.41
|ORtxt=[0.26-0.59] cm taller
|OA=1
}}

{{PMID Auto GWAS
|PMID=19448621
|Trait=Menarche and menopause (age at onset)
|Title=Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
|RiskAllele=A
|Pval=3E-13
|OR=0.16
|ORtxt=[0.12-0.20] years older
|OA=1
}}

{{PMID Auto GWAS
|PMID=20303062
|Trait=Digit length ratio
|Title=A Variant in LIN28B Is Associated with 2D:4D Finger-Length Ratio, a Putative Retrospective Biomarker of Prenatal Testosterone Exposure
|RiskAllele=A
|Pval=0.000002
|OR=0.63
|ORtxt=[0.41-0.85] increase in mean 2D:4D
|OA=1
}}

{{omim
|desc=FINGERS, RELATIVE LENGTH OF
|id=136100
|rsnum=314277
}}

{{omim
|id=606255
|rsnum=314277
}}

{{omim
|id=612882
|rsnum=314277
}}

{{PMID Auto
|PMID=22822098
|Title=Functional Study of Risk Loci of Stem Cell-associated Gene Lin-28B and Associations with Disease Survival Outcomes in Epithelial Ovarian Cancer
}}

{{PMID Auto
|PMID=19030899
|Title=Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.
|OA=1
}}

{{PMID Auto
|PMID=19448622
|Title=Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche.
}}

{{PMID Auto
|PMID=20398887
|Title=Distinct variants at LIN28B influence growth in height from birth to adulthood.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs314277
|overall_frequency_n=97
|overall_frequency_d=128
|overall_frequency=0.757812
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=81
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23508249
|Title=Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}