{{Rsnum
|rsid=31489
|Gene=CLPTM1L
|Chromosome=5
|position=1342599
|Orientation=plus
|GMAF=0.3503
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=CLPTM1L
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 16.1 | 46.4 | 37.5
| HCB | 2.2 | 27.7 | 70.1
| JPT | 1.8 | 22.1 | 76.1
| YRI | 30.6 | 50.3 | 19.0
| ASW | 19.3 | 49.1 | 31.6
| CHB | 2.2 | 27.7 | 70.1
| CHD | 2.8 | 27.5 | 69.7
| GIH | 2.0 | 29.7 | 68.3
| LWK | 16.4 | 49.1 | 34.5
| MEX | 1.7 | 37.9 | 60.3
| MKK | 16.0 | 44.9 | 39.1
| TSI | 10.8 | 57.8 | 31.4
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19836008
|Trait=Lung adenocarcinoma
|Title=A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma
|RiskAllele=C
|Pval=2E-10
|OR=1.12
|ORtxt=[1.09-1.16]
|OA=1
}}

{{PMID Auto
|PMID=20142248
|Title=Cumulative effect of multiple Loci on genetic susceptibility to familial lung cancer
|OA=1
}}

{{PMID Auto
|PMID=21622582
|Title=The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema
}}

{{PMID Auto
|PMID=22404340
|Title=Replication of results of genome-wide association studies on lung cancer susceptibility loci in a Korean population
}}

{{PMID Auto
|PMID=22675468
|Title=Functional Characterization of CLPTM1L as a Lung Cancer Risk Candidate Gene in the 5p15.33 Locus
|OA=1
}}

{{PMID Auto
|PMID=18978790
|Title=Lung cancer susceptibility locus at 5p15.33.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs31489
|overall_frequency_n=43
|overall_frequency_d=128
|overall_frequency=0.335938
|n_genomes=32
|n_genomes_annotated=0
|n_haplomes=37
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=24039754
|Title=The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer
|OA=1
}}

{{PMID Auto
|PMID=24615522
|Title=Quantitative assessment of common genetic variants on chromosome 5p15 and lung cancer risk
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}