{{Rsnum
|rsid=3213094
|Gene=IL12B
|Chromosome=5
|position=159323761
|Orientation=minus
|GMAF=0.3398
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IL12B
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 36.3 | 62.8
| HCB | 14.6 | 54.0 | 31.4
| JPT | 31.9 | 44.2 | 23.9
| YRI | 12.9 | 44.2 | 42.9
| ASW | 12.3 | 35.1 | 52.6
| CHB | 14.6 | 54.0 | 31.4
| CHD | 22.9 | 45.9 | 31.2
| GIH | 12.9 | 38.6 | 48.5
| LWK | 17.3 | 49.1 | 33.6
| MEX | 20.0 | 38.2 | 41.8
| MKK | 6.4 | 42.3 | 51.3
| TSI | 7.8 | 36.3 | 55.9
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/01/26/snpwatch-new-psoriasis-snps-found-for-both-europeans-and-asians/ 23andMe blog] [[psoriasis]] 
Chinese
*[[rs3213094]](C) 	1.28x risk

{{PMID Auto GWAS
|PMID=19169255
|Trait=Psoriasis
|Title=Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
|RiskAllele=A
|Pval=3E-26
|OR=1.28
|ORtxt=[1.23-1.35]
}}

{{omim
|desc=PSORIASIS SUSCEPTIBILITY 11; PSORS11
|id=612599
|rsnum=3213094
}}

{{PharmGKB
|RSID=rs3213094
|Name_s=
|Gene_s=IL12B
|Feature=
|Evidence=PubMed ID:19169255; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. (Initial Sample Size: 1,139 Chinese cases, 1,132 Chinese controls; Replication Sample Size: 5,721 Chinese cases, 7,340 Chinese controls); (Region: 5q33.3; Reported Gene(s): IL12B; Risk Allele: rs3213094-A); (p-value= 3E-26).This variant is associated with Psoriasis.
|Drugs=
|Drug Classes=
|Diseases=Psoriasis
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740045
}}

{{PMID Auto GWAS
|PMID=20953190
|Trait=None
|Title=A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
|RiskAllele=
|Pval=5E-11
|OR=1.3900
|ORtxt=[1.26-1.53]
|OA=1
}}

{{PMID Auto
|PMID=21463712
|Title=Differential serum cytokine levels are associated with cytokine gene polymorphisms in North Indians with active pulmonary tuberculosis
}}

{{PMID Auto
|PMID=20606885
|Title=Genetics of psoriasis and psoriatic arthritis.
|OA=1
}}

{{PMID Auto
|PMID=21253569
|Title=Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3213094
|overall_frequency_n=37
|overall_frequency_d=128
|overall_frequency=0.289062
|n_genomes=30
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}