{{Rsnum
|rsid=3213207
|Gene=DTNBP1
|Chromosome=6
|position=15627871
|Orientation=minus
|GMAF=0.06795
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DTNBP1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 79.6 | 18.6 | 1.8
| HCB | 97.1 | 2.9 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 94.6 | 5.4 | 0.0
| ASW | 89.5 | 10.5 | 0.0
| CHB | 97.1 | 2.9 | 0.0
| CHD | 97.2 | 2.8 | 0.0
| GIH | 86.1 | 10.9 | 3.0
| LWK | 90.0 | 8.2 | 1.8
| MEX | 89.7 | 10.3 | 0.0
| MKK | 92.3 | 7.7 | 0.0
| TSI | 78.4 | 20.6 | 1.0
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19252939
|Title=Dysbindin gene (DTNBP1) and schizophrenia in Korean population
}}

{{PharmGKB
|RSID=rs3213207
|Name_s=
|Gene_s=DTNBP1
|Feature=
|Evidence=PubMed ID:17192893; PubMed ID:17555717; PubMed ID:18162312
|Annotation=Several studies showed an associaction of this SNP in DTNBP1 with schizophrenia and other psychotic disorders, including substance-induced psychosis
|Drugs=methamphetamine
|Drug Classes=
|Diseases=Bipolar Disorder; Psychotic Disorders; Schizophrenia
|Curation Level=Curated
|PharmGKB Accession ID=PA162191366
}}

{{PMID Auto
|PMID=12474144
|Title=Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families.
|OA=1
}}

{{PMID Auto
|PMID=14618545
|Title=The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.
|OA=1
}}

{{PMID Auto
|PMID=15290652
|Title=A powerful strategy to account for multiple testing in the context of haplotype analysis.
|OA=1
}}

{{PMID Auto
|PMID=17033966
|Title=Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.
|OA=1
}}

{{PMID Auto
|PMID=17264804
|Title=Dysbindin associated with selective serotonin reuptake inhibitor antidepressant efficacy.
}}

{{PMID Auto
|PMID=17445278
|Title=Association between the DTNBP1 gene and intelligence: a case-control study in young patients with schizophrenia and related disorders and unaffected siblings.
|OA=1
}}

{{PMID Auto
|PMID=17476109
|Title=DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.
|OA=1
}}

{{PMID Auto
|PMID=17888175
|Title=Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia.
|OA=1
}}

{{PMID Auto
|PMID=17964051
|Title=Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder.
}}

{{PMID Auto
|PMID=18562100
|Title=DTNBP1 haplotype influences baseline assessment scores of schizophrenic in-patients.
}}

{{PMID Auto
|PMID=18663367
|Title=The dystrobrevin-binding protein 1 gene: features and networks.
|OA=1
}}

{{PMID Auto
|PMID=18715757
|Title=Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.
|OA=1
}}

{{PMID Auto
|PMID=18797396
|Title=Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.
}}

{{PMID Auto
|PMID=19065121
|Title=Dysbindin gene (DTNBP1) in major depression: association with clinical response to selective serotonin reuptake inhibitors.
}}

{{PMID Auto
|PMID=19089808
|Title=Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS).
}}

{{PMID Auto
|PMID=19729970
|Title=Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia.
}}

{{PMID Auto
|PMID=19911060
|Title=Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.
|OA=1
}}

{{PMID Auto
|PMID=20046352
|Title=Effect of the dysbindin gene on antimanic agents in patients with bipolar I disorder.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3213207
|n_genomes=8
|n_genomes_annotated=0
|n_haplomes=9
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}