{{Rsnum
|rsid=3217992
|Gene=CDKN2B
|Chromosome=9
|position=22003224
|Orientation=minus
|GMAF=0.3595
|Gene_s=CDKN2B,CDKN2B-AS1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 16.2 | 42.3 | 41.4
| HCB | 23.5 | 50.7 | 25.7
| JPT | 33.9 | 45.5 | 20.5
| YRI | 2.1 | 18.5 | 79.5
| ASW | 3.5 | 28.1 | 68.4
| CHB | 23.5 | 50.7 | 25.7
| CHD | 24.3 | 48.6 | 27.1
| GIH | 18.8 | 48.5 | 32.7
| LWK | 0.0 | 17.4 | 82.6
| MEX | 16.1 | 50.0 | 33.9
| MKK | 1.3 | 26.6 | 72.1
| TSI | 17.6 | 50.0 | 32.4
| HapMapRevision=28
}}
[[rs3217992]] is a SNP in the cyclin-dependent kinase inhibitor 2B [[CDKN2B]] gene.

A study of 432 Han Chinese patients with myocardial infarctions concluded that male subjects carrying a [[rs3217992]](A) allele were at 1.24x increased risk (for MI).{{PMID|19272367}}

{{PMID Auto
|PMID=19559344
|Title=Genetic variants on chromosome 9p21 and ischemic stroke in Chinese
}}

{{PMID Auto
|PMID=20978019
|Title=CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection
}}

{{PMID|17459456|OA=1
}} A common variant of the p16(INK4a) genetic region is associated with physical function in older people.

{{PMID|18174243|OA=1
}} Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

{{PMID|19258477|OA=1
}} Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

{{PMID|20386740|OA=1
}} Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.

{{PMID Auto
|PMID=23111177
|Title=CDKN2B-AS1 Genotype-Glaucoma Feature Correlations in Primary Open-Angle Glaucoma Patients From the United States
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}