{{Rsnum
|rsid=3219489
|Gene=MUTYH
|Chromosome=1
|position=45331833
|Orientation=minus
|GMAF=0.3186
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=MUTYH
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 1.6 | 57.1 | 41.3
| HCB | 15.6 | 60.0 | 24.4
| JPT | 14.3 | 61.9 | 23.8
| YRI | 8.1 | 45.2 | 46.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 15.6 | 60.0 | 24.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20149637
|Title=Common variants in human CRC genes as low-risk alleles
}}

{{PMID Auto
|PMID=22641385
|Title=Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer
}}
{{PMID|16465622|OA=1
}} Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.

{{PMID|18547414|OA=1
}} Genotyping panel for assessing response to cancer chemotherapy.

{{PMID|18823566|OA=1
}} Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.

{{PMID|19443904|OA=1
}} Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.

{{PMID|19536092|OA=1
}} Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.

{{PMID|19781088|OA=1
}} Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.

{{PMID|21195504}} Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk.

{{PMID|22469746}} Association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and age-related macular degeneration.

{{PMID Auto
|PMID=22720119
|Title=Association of base excision repair gene polymorphisms with ESRD risk in a Chinese population
|OA=1
}}
{{GET Evidence
|gene=MUTYH
|aa_change=Gln311His
|aa_change_short=Q311H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3219489
|overall_frequency_n=2720
|overall_frequency_d=10754
|overall_frequency=0.252929
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.017
|genetests_testable=Y
|nblosum100=-1
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=22466227
|Title=Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.
}}

{{ClinVar
|ALT=G
|CHROM=1
|CLNACC=RCV000034684.1; RCV000079500.2
|CLNALLE=1
|CLNDBN=not provided; AllHighlyPenetrant
|CLNDSDB=MedGen
|CLNDSDBID=CN169374
|CLNHGVS=NC_000001.11:g.45331833C>G
|CLNORIGIN=1
|CLNSIG=2
|CLNSRC=ClinVar; Emory University
|CLNSRCID=NM_001128425.1:c.1014G>C; 2340
|Disease=not provided; AllHighlyPenetrant
|FwdALT=C
|FwdREF=G
|GENEINFO=MUTYH:4595
|GENE_ID=4595
|GENE_NAME=MUTYH
|REF=C
|RSPOS=45331833
|Reversed=1
|SAO=0
|SSR=0
|Tags=RV;PM;PMC;S3D;SLO;NSM;REF;ASP;VLD;G5A;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3
|VC=SNV
|VP=0x050328000a0517051f000100
|WGT=1
|dbSNPBuildID=106
|rsid=3219489
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}