{{Rsnum
|rsid=327127
|Chromosome=13
|position=28944763
|Orientation=plus
|GMAF=0.1589
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 90.8 | 9.2 | 0.0
| HCB | 71.1 | 26.7 | 2.2
| JPT | 77.3 | 18.2 | 4.5
| YRI | 46.0 | 46.0 | 7.9
| ASW | 0.0 | 0.0 | 0.0
| CHB | 71.1 | 26.7 | 2.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs327127
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Smoking Initiation (p = 0.00002283; OR for minor allele C:0.623)
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920608
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs327127
|overall_frequency_n=107
|overall_frequency_d=128
|overall_frequency=0.835938
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=91
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}