{{Rsnum
|rsid=331
|Gene=LPL
|Chromosome=8
|position=19962894
|Orientation=plus
|GMAF=0.2695
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LPL
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 10.7 | 30.4 | 58.9
| HCB | 2.9 | 30.1 | 66.9
| JPT | 7.1 | 27.4 | 65.5
| YRI | 10.3 | 53.4 | 36.3
| ASW | 9.1 | 52.7 | 38.2
| CHB | 2.9 | 30.1 | 66.9
| CHD | 5.5 | 33.0 | 61.5
| GIH | 2.0 | 28.7 | 69.3
| LWK | 14.5 | 39.1 | 46.4
| MEX | 6.9 | 34.5 | 58.6
| MKK | 14.1 | 54.5 | 31.4
| TSI | 8.8 | 34.3 | 56.9
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs331
|Name_s=
|Gene_s=LPL
|Feature=
|Evidence=PubMed ID:19802338
|Annotation=Phenotype: In a GWAS, this SNP was significantly associated with plasma concentrations of triglycerides and Apolipoprotein A1. Study size:6382. Study population/ethnicity: Caucasian women. Significance metric(s): triglycerides: p = 1.7 x 10(-9); ApoA1: p = 4.0 x 10(-8). Type of association: CO; GN
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA165111810
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19148283
|Title=Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=19299407
|Title=Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
|OA=1
}}

{{PMID Auto
|PMID=19913121
|Title=Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs331
|overall_frequency_n=36
|overall_frequency_d=128
|overall_frequency=0.28125
|n_genomes=25
|n_genomes_annotated=0
|n_haplomes=29
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}