{{Rsnum
|rsid=33981382
|Gene=PADI4
|Chromosome=1
|position=17342393
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.006887
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PADI4
}}{{Venter SNP
|rsid=33981382
|allele=G
|frequency=
|uid=1103675034022
|type=heterozygous_SNP
|hugo=PADI4
|ensembl gene=ENSG00000159339
|ensembl transcript=ENST00000290507
|sift=AFFECT FUNCTION
|disease=PADI4 is thought to be a rheumatoid arthritis susceptibility locus (MIM:180300). Could have an important role in the pathogenesis of rheumatoid arthritis by increasing citrullination of proteins in rheumatoid arthritis synovial tissues, leading, in a cytokine-rich milieu, to a break in tolerance to citrullinated peptides processed and presented in the appropriate HLA context.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}