{{Rsnum
|rsid=34516635
|Gene=IGF1R
|Chromosome=15
|position=98908747
|Orientation=plus
|Summary=Longevity and height for Ashkenazi Jewish women.
|geno1=(G;G)
|geno2=(A;G)
|geno3=(A;A)
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=IGF1R
}}[[rs34516635]] is one of a small number of (rare) SNPs in the [[IGF1R]] gene found in a study of 384 [[Ashkenazi]] centenarians to potentially be associated with longevity and [[ageing]]. The [[rs34516635]](A) allele was found somewhat more frequently (p=0.02) in female centenarians than in controls. No association was found for males. Higher IGF1 levels and an average decrease in maximal lifetime [[appearance|height]] of 2.5cm were also reported to be associated with (female Ashkenazi) centenarians.{{PMID|18316725|OA=1
}}

{{PMID Auto
|PMID=20625407
|Title=A comprehensive in silico analysis of the functional and structural impact of SNPs in the IGF1R gene.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}