{{Rsnum
|rsid=352140
|Gene=TLR9
|Chromosome=3
|position=52222681
|Orientation=plus
|ReferenceAllele=A
|GMAF=0.4573
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TLR9
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 27.4 | 49.6 | 23.0
| HCB | 34.6 | 50.7 | 14.7
| JPT | 30.1 | 43.4 | 26.5
| YRI | 47.6 | 44.9 | 7.5
| ASW | 44.6 | 46.4 | 8.9
| CHB | 34.6 | 50.7 | 14.7
| CHD | 34.9 | 54.1 | 11.0
| GIH | 32.7 | 44.6 | 22.8
| LWK | 48.1 | 43.5 | 8.3
| MEX | 19.0 | 51.7 | 29.3
| MKK | 46.8 | 37.8 | 15.4
| TSI | 13.7 | 38.2 | 48.0
| HapMapRevision=28
}}{{PMID|19130296}} T allele was significantly associated with the susceptibility to [[SLE]] (Z = 2.357, P = 0.018402) in dominant model

{{PMID Auto
|PMID=19455129
|Title=Epistasis Between Toll-Like Receptor-9 Polymorphisms and Variants in NOD2 and IL23R Modulates Susceptibility to Crohn's Disease
}}

{{PMID Auto
|PMID=20140383
|Title=Candidate gene analysis of ocular toxoplasmosis in Brazil: evidence for a role for toll-like receptor 9 (TLR9)
}}
{{PMID Auto
|PMID=20497632
|Title=Association of TLR9 gene polymorphisms with lupus nephritis in a Chinese Han population
}}
{{PMID Auto
|PMID=20500814
|Title=Toll-like receptor 9 polymorphisms influence mother-to-child transmission of human immunodeficiency virus type 1
|OA=1
}}
{{PMID Auto
|PMID=21050493
|Title=Toll-Like Receptor Gene Polymorphisms are Associated with Susceptibility to Graves' Ophthalmopathy in Taiwan Males
|OA=1
}}
{{PMID Auto
|PMID=21132533
|Title=Evaluation of Toll-like receptors 3 (c.1377C/T) and 9 (G2848A) gene polymorphisms in cervical cancer susceptibility
}}

{{PMID Auto
|PMID=21633947
|Title=Polymorphisms in the toll-like receptor 9 gene associated with sepsis and multiple organ dysfunction after major blunt trauma
}}

{{PMID Auto
|PMID=21689850
|Title=Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood
|OA=1
}}

{{PMID Auto
|PMID=22311043
|Title=Association of Toll-like receptor (TLR) 2, 3 and 9 genes polymorphism with prostate cancer risk in North Indian population
}}

{{PMID Auto
|PMID=22228476
|Title=Lack of association of Toll-like receptor 9 polymorphisms with susceptibility to systemic lupus erythematosus in an Asian population: a meta-analysis.
}}

{{PMID Auto
|PMID=22065095
|Title=TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from Southern Brazil.
}}

{{PMID Auto
|PMID=22594374
|Title=Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study
|OA=1
}}

{{PMID Auto
|PMID=22714906
|Title=Involvement of toll-like receptor 9 polymorphism in cervical cancer development
|OA=1
}}

{{PMID Auto
|PMID=22717578
|Title=TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism
|OA=1
}}

{{PMID Auto
|PMID=16859562
|Title=Do host genetic traits in the bacterial sensing system play a role in the development of Chlamydia trachomatis-associated tubal pathology in subfertile women?
|OA=1
}}

{{PMID Auto
|PMID=18396467
|Title=Genetic variation and haplotype structures of innate immunity genes in eastern India.
|OA=1
}}

{{PMID Auto
|PMID=18776126
|Title=Toll-like receptor 9 affects severity of IgA nephropathy.
|OA=1
}}

{{PMID Auto
|PMID=19134200
|Title=No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.
|OA=1
}}

{{PMID Auto
|PMID=19284650
|Title=TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression.
|OA=1
}}

{{PMID Auto
|PMID=19505919
|Title=Toll-like receptor signaling pathway variants and prostate cancer mortality.
|OA=1
}}

{{PMID Auto
|PMID=20041166
|Title=Common genetic variation and the control of HIV-1 in humans.
|OA=1
}}

{{PMID Auto
|PMID=21595536
|Title=Investigation of association between TLR9 gene polymorphisms and VKH in Japanese patients.
}}

{{PMID Auto
|PMID=21778277
|Title=Tonsillar TLR9 expression and efficacy of tonsillectomy with steroid pulse therapy in IgA nephropathy patients.
}}

{{PMID Auto
|PMID=21872627
|Title=Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
}}

{{PMID Auto
|PMID=23816930
|Title=Toll-like receptor 9 (TLR9) gene polymorphisms associated with increased susceptibility of human papillomavirus-16 infection in patients with cervical cancer
}}

{{PMID Auto
|PMID=23964786
|Title=Toll-like receptor 9 SNPs are susceptible to the development and progression of membranous glomerulonephritis: 27 years follow-up in Taiwan
}}

{{PMID Auto
|PMID=24004541
|Title=Association study of TLR-9 polymorphisms and systemic lupus erythematosus in Northern Chinese Han population
}}

{{PMID Auto
|PMID=24224717
|Title=Genetic variation in toll-like receptors and retinoic acid-inducible gene I and outcome of hepatitis C virus infection: a candidate gene association study
}}

{{PMID Auto
|PMID=22948541
|Title=Contribution of toll-like receptor 9 gene single-nucleotide polymorphism to systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=23065292
|Title=Toll-like receptor polymorphisms and vasculitis susceptibility: meta-analysis and systematic review.
}}

{{PMID Auto
|PMID=23071570
|Title=Gene-gene interaction and functional impact of polymorphisms on innate immune genes in controlling Plasmodium falciparum blood infection level.
|OA=1
}}

{{PMID Auto
|PMID=23592712
|Title=Genetics of toll like receptor 9 in ANCA associated vasculitides.
}}

{{PMID Auto
|PMID=23990988
|Title=The TLR9 gene polymorphisms and the risk of cancer: evidence from a meta-analysis
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}