{{Rsnum
|rsid=35229355
|Chromosome=6
|position=155608667
|Orientation=plus
|GMAF=0.1396
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 97.3 | 2.7 | 0.0
| HCB | 31.4 | 50.4 | 18.2
| JPT | 43.4 | 46.9 | 9.7
| YRI | 78.9 | 19.0 | 2.0
| ASW | 86.0 | 14.0 | 0.0
| CHB | 31.4 | 50.4 | 18.2
| CHD | 35.8 | 50.5 | 13.8
| GIH | 88.1 | 11.9 | 0.0
| LWK | 89.1 | 10.0 | 0.9
| MEX | 89.7 | 10.3 | 0.0
| MKK | 89.1 | 10.3 | 0.6
| TSI | 99.0 | 1.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19176441
|Trait=Treatment response for acute lymphoblastic leukemia
|Title=Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
|RiskAllele=T
|Pval=0.000005
|OR=7.24
|ORtxt=[2.46-21.30]
|OA=1
}}

{{PharmGKB
|RSID=rs35229355
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19176441; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. (Initial Sample Size: 487 children; Replication Sample Size: NR); (Region: 6q25.3; Reported Gene(s): intergenic; Risk Allele: rs35229355-T); (p-value= 0.000005).This variant is associated with Treatment response for acute lymphoblastic leukemia.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740028
}}

{{PharmGKB
|RSID=rs35229355
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19176441
|Annotation=This variant is associated with end-of-induction minimal risidual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) from 2 independent cohorts (GWAS result). Risk Allele: T, MAF= 0.03, combined P value= 4.96E-06.
|Drugs=
|Drug Classes=
|Diseases=Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA162470158
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs35229355
|overall_frequency_n=8
|overall_frequency_d=128
|overall_frequency=0.0625
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=7
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}