{{Rsnum
|rsid=353016
|Gene=SNAP25
|Orientation=plus
|geno1=(T;T)
|geno2=(C;T)
|geno3=(C;C)
|Chromosome=4
|position=74015033
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Status=Merged
|Merged=352054
}}SNPs in the [[SNAP25]] gene were initially {{PMID|17160701}} linked to [[intelligence]] but have failed to replicate {{PMID|19418213}}.

While now suspect, the original work can be found in {{PMID|16801949}}.

The (T;T) genotype averages almost 3 PIQ points higher than the (C;T) genotype, which averages almost 3 PIQ points higher than the (C;C) genotype.{{PMID|17908175}}

[[rs353016]] is in close linkage with [[rs363050]], with r2 = 0.98, such that the [[rs363050(A)]] allele typically is linked to the [[rs353016(T)]] allele. For SNPs [[rs363039]] - [[rs363043]] - [[rs353016]], respectively, the haplotype C-T-T is most associated with higher intelligence in children, whereas the haplotype C-C-T is most associated in adults (SNPs oriented as in dbSNP). {{PMID|17908175}}