{{Rsnum
|rsid=35424040
|Chromosome=11
|Orientation=plus
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=HBB
|position=5226940
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=HBB
}}{{omim
|id=141900
|rsnum=35424040
|variant=0149
}}

{{ClinVar
|rsid=35424040
|Reversed=1
|FwdREF=G
|FwdALT=A,C,T
|REF=C
|ALT=A,G,T
|RSPOS=5248170
|CHROM=11
|dbSNPBuildID=126
|SSR=0
|SAO=1
|VP=0x050368000000000502110104
|GENEINFO=HBB:3043
|GENE_NAME=HBB
|GENE_ID=3043
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000011.9:g.5248170C>A
|CLNORIGIN=1
|CLNSIG=255
|Tags=RV;PM;PMC;S3D;SLO;HD;GNO;OTHERKG;LSD;OM;NOV
|CLNACC=RCV000016439.1; RCV000016440.24; RCV000016441.24
|CLNDBN=HEMOGLOBIN KNOSSOS; Beta-plus-thalassemia; Beta-knossos-thalassemia
|CLNSRC=GTR; OMIM Allelic Variant
|CLNSRCID=GTR000500319; 141900.0149
|Disease=HEMOGLOBIN KNOSSOS; Beta-plus-thalassemia; Beta-knossos-thalassemia
}}

{{PMID Auto
|PMID=2467892
|Title=Beta-thalassemia intermedia in two Turkish families is caused by the interaction of Hb Knossos [beta 27(B9)Ala----Ser] and of Hb City of Hope [beta 69(E13)Gly----ser] with beta (0)-thalassemia.
}}

{{PMID Auto
|PMID=3942130
|Title=Hemoglobin Knossos: a clinical, laboratory, and epidemiological study.
}}

{{PMID Auto
|PMID=3955238
|Title=Homozygous hemoglobin Knossos (alpha 2 beta 227(B9) Ala----Ser): a new variety of beta (+)-thalassemia intermedia associated with delta (0)-thalassemia.
}}

{{PMID Auto
|PMID=6733281
|Title=Abnormal processing of beta Knossos RNA.
}}

{{PMID Auto
|PMID=7104238
|Title='Silent' beta-thalassaemia caused by a 'silent' beta-chain mutant: the pathogenesis of a syndrome of thalassaemia intermedia.
}}

{{PMID Auto
|PMID=7173395
|Title=Structural study of hemoglobin Knossos, beta 27 (B9) Ala leads to Ser. A new abnormal hemoglobin present as a silent beta-thalassemia.
}}

{{on chip | HumanOmni1Quad}}