{{Rsnum
|rsid=356165
|Gene=SNCA
|Chromosome=4
|position=89725735
|Orientation=plus
|GMAF=0.4885
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SNCA
}}[[rs356165]] is a SNP in the 3' UTR of the alpha-synuclein [[SNCA]] gene. It has been associated in some studies, and not others, with Parkinson's disease.

{{PMID|20478361}} A study of 330 Chinese with Parkinson's found no association with [[rs356165]] and risk for Parkinson's.

{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 32.3 | 49.2 | 18.5
| HCB | 18.2 | 54.5 | 27.3
| JPT | 20.9 | 41.9 | 37.2
| YRI | 6.3 | 36.5 | 57.1
| ASW | 0.0 | 0.0 | 0.0
| CHB | 18.2 | 54.5 | 27.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=18485051
|Title=Multiple alpha-synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population.
}}

{{PMID Auto
|PMID=22076805
|Title=A Search for SNCA 3' UTR Variants Identified SNP rs356165 as a Determinant of Disease Risk and Onset Age in Parkinson's Disease
}}

{{PMID Auto
|PMID=22451204
|Title=Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2
|OA=1
}}

{{PMID|15637659|OA=1
}} Linkage disequilibrium patterns and tagSNP transferability among European populations.

{{PMID|17531291|OA=1
}} Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease.

{{PMID|17872362}} alpha-Synuclein and Parkinson disease susceptibility.

{{PMID|19063963|OA=1
}} Genetic susceptibility in Parkinson's disease.

{{PMID|19771175|OA=1
}} Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

{{PMID|19890971}} Alpha-synuclein polymorphisms are associated with Parkinson's disease in a Saskatchewan population.

{{PMID|22291217|OA=1
}} An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}