{{Rsnum
|rsid=358806
|Chromosome=3
|position=55279372
|Orientation=plus
|GMAF=0.1873
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 5.3 | 35.4 | 59.3
| HCB | 2.2 | 27.7 | 70.1
| JPT | 8.0 | 43.4 | 48.7
| YRI | 0.0 | 17.0 | 83.0
| ASW | 1.8 | 22.8 | 75.4
| CHB | 2.2 | 27.7 | 70.1
| CHD | 0.9 | 27.5 | 71.6
| GIH | 1.0 | 17.8 | 81.2
| LWK | 0.9 | 12.0 | 87.0
| MEX | 1.8 | 24.6 | 73.7
| MKK | 0.0 | 10.3 | 89.7
| TSI | 5.9 | 26.5 | 67.6
| HapMapRevision=28
}}[[rs358806]] has been reported in a large study to be associated with [[type-2 diabetes]]. The risk allele is (C); the odds ratio associated with heterozygotes is 0.86 (CI 0.75-0.97), and for homozygotes, 1.78 (CI 1.34-2.36). {{PMID|17554300|OA=1
}}

{{GWAS Summary
|SNP=rs358806
|PubMedID=17554300
|Condition=Type 2 diabetes
|Gene=NR
|Risk Allele=
|pValue=3.00E-006
|OR=1.16
|95CI=1.03-1.33
|OA=1
}}

{{PharmGKB
|RSID=rs358806
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,924 cases, 2,938 controls; Replication Sample Size: (see Zeggini 2007)). This variant is associated with Type 2 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus; Diabetes Mellitus, Type 2
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356507
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs358806
|overall_frequency_n=115
|overall_frequency_d=128
|overall_frequency=0.898438
|n_genomes=54
|n_genomes_annotated=0
|n_haplomes=100
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}