{{Rsnum
|rsid=362691
|Gene=RELN
|Chromosome=7
|position=103610714
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=G
|GMAF=0.1033
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=RELN
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 3.1 | 24.6 | 72.3
| HCB | 2.2 | 20.0 | 77.8
| JPT | 0.0 | 18.2 | 81.8
| YRI | 1.6 | 14.3 | 84.1
| ASW | 0.0 | 0.0 | 0.0
| CHB | 2.2 | 20.0 | 77.8
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=362691
|allele=C
|frequency=0.133
|uid=1103652662160
|type=heterozygous_SNP
|hugo=RELN
|ensembl gene=ENSG00000189056
|ensembl transcript=ENST00000343529
|sift=TOLERATED
|disease=Defects in RELN may predispose to autistic disorder. A polymorphic GGC triplet repeat located in the 5' UTR region of RELN gene, which harbors in the normal population 8 to 10 repeats, is significantly increased in autistic patients to carry 4 to 23 additional repeats.
}}
{{PMID Auto
|PMID=20554015
|Title=No significant association between RELN polymorphism and autism in case-control and family-based association study in Chinese Han population
}}{{PMID Auto
|PMID=18597938
|Title=Genetic analysis of reelin gene (RELN) SNPs: no association with autism spectrum disorder in the Indian population.
}}

{{PMID Auto
|PMID=20697953
|Title=An association analysis of reelin gene (RELN) polymorphisms with childhood epilepsy in eastern Indian population from West Bengal.
}}{{GET Evidence
|gene=RELN
|aa_change=Leu997Val
|aa_change_short=L997V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs362691
|overall_frequency_n=1032
|overall_frequency_d=10758
|overall_frequency=0.0959286
|n_genomes=7
|n_genomes_annotated=0
|n_haplomes=9
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.25
|nblosum100=0
|autoscore=0
|webscore=N
}}{{PMID Auto
|PMID=23216241
|Title=Association analysis of two single-nucleotide polymorphisms of the RELN gene with autism in the South African population.
|OA=1
}}