{{Rsnum
|rsid=363039
|Gene=SNAP25
|Chromosome=20
|position=10239848
|Orientation=plus
|GMAF=0.4467
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=SNAP25
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 38.1 | 46.9 | 15.0
| HCB | 16.9 | 44.9 | 38.2
| JPT | 15.9 | 54.9 | 29.2
| YRI | 30.6 | 50.3 | 19.0
| ASW | 29.8 | 52.6 | 17.5
| CHB | 16.9 | 44.9 | 38.2
| CHD | 23.4 | 50.5 | 26.2
| GIH | 42.6 | 46.5 | 10.9
| LWK | 30.0 | 51.8 | 18.2
| MEX | 21.1 | 59.6 | 19.3
| MKK | 21.8 | 57.1 | 21.2
| TSI | 34.3 | 48.0 | 17.6
| HapMapRevision=28
}}

This is one of four SNPs in the first intron of the [[SNAP25]] gene that have been correlated with increased [[intelligence]] based on studies of ~300 Caucasian subjects.{{PMID|16801949}}

In orientation to the dbSNP entry for this SNP, rather than as published, the (C;C) genotype averages ~2 PIQ points higher than the (C;T) genotype, which averages 2 PIQ points higher than the (T;T) genotype.{{PMID|16801949}}

For SNPs [[rs363039]] - [[rs363043]] - [[rs353016]], respectively, the haplotype C-T-T is most associated with higher intelligence in children, whereas the haplotype C-C-T is most associated in adults (SNPs oriented as in dbSNP). {{PMID|17908175}}

{{PMID Auto
|PMID=20950795
|Title=The SNAP25 Gene Is Linked to Working Memory Capacity and Maturation of the Posterior Cingulate Cortex During Childhood
}}

{{PMID Auto
|PMID=22193912
|Title=Variants in SNAP25 are targets of natural selection and influence verbal performances in women
}}

{{PMID Auto
|PMID=23593184
|Title=DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}