{{Rsnum
|rsid=363043
|Gene=SNAP25
|Chromosome=20
|position=10245498
|Orientation=plus
|GMAF=0.2328
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=SNAP25
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 49.6 | 41.6 | 8.8
| HCB | 99.3 | 0.7 | 0.0
| JPT | 99.1 | 0.9 | 0.0
| YRI | 36.1 | 49.0 | 15.0
| ASW | 35.1 | 49.1 | 15.8
| CHB | 99.3 | 0.7 | 0.0
| CHD | 99.1 | 0.9 | 0.0
| GIH | 65.3 | 31.7 | 3.0
| LWK | 44.5 | 41.8 | 13.6
| MEX | 72.4 | 24.1 | 3.4
| MKK | 30.1 | 54.5 | 15.4
| TSI | 49.0 | 41.2 | 9.8
| HapMapRevision=28
}}
SNPs in the [[SNAP25]] gene were initially {{PMID|17160701}} linked to [[intelligence]] but have failed to replicate {{PMID|19418213}}.

While now suspect, the original work can be found in {{PMID|16801949}}.

The (T;T) genotype averages several PIQ points higher than the (C;T) genotype, which averages several PIQ points higher than the (C;C) genotype. {{PMID|17908175}}

For SNPs [[rs363039]] - [[rs363043]] - [[rs353016]], respectively, the haplotype C-T-T is most associated with higher intelligence in children, whereas the haplotype C-C-T is most associated in adults (SNPs oriented as in dbSNP). {{PMID|17908175}}

{{PMID Auto
|PMID=21497654
|Title=SNAP-25 single nucleotide polymorphisms are associated with hyperactivity in autism spectrum disorders.
}}

{{PMID Auto
|PMID=23593184
|Title=DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}