{{Rsnum
|rsid=3732379
|Gene=CX3CR1
|Chromosome=3
|position=39265765
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.174
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CX3CR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 54.9 | 38.1 | 7.1
| HCB | 97.8 | 2.2 | 0.0
| JPT | 91.2 | 8.8 | 0.0
| YRI | 82.3 | 16.3 | 1.4
| ASW | 78.9 | 21.1 | 0.0
| CHB | 97.8 | 2.2 | 0.0
| CHD | 97.2 | 2.8 | 0.0
| GIH | 73.3 | 24.8 | 2.0
| LWK | 84.5 | 15.5 | 0.0
| MEX | 58.6 | 34.5 | 6.9
| MKK | 76.3 | 23.1 | 0.6
| TSI | 54.5 | 37.6 | 7.9
| HapMapRevision=28
}}
see also [[rs3732378]]

{{omim
|desc=HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, RAPID PROGRESSION TO AIDS
|id=601470
|rsnum=3732379
|variant=0001
}}

{{ClinVar
|rsid=3732379
|Reversed=0
|FwdREF=C
|FwdALT=T
|REF=C
|ALT=T
|RSPOS=39307256
|CHROM=3
|GMAF=0.174
|dbSNPBuildID=107
|SSR=0
|SAO=0
|VP=0x05036800000015051f110100
|GENEINFO=CX3CR1:1524
|GENE_NAME=CX3CR1
|GENE_ID=1524
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000003.11:g.39307256C>T
|CLNSIG=255
|Tags=PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.826; 0.174
|CLNACC=RCV000008629.1; RCV000008630.1; RCV000022393.1; RCV000023109.1
|CLNDBN=Human immunodeficiency virus type 1, rapid progression to AIDS; Coronary artery disease, resistance to; Age-related macular degeneration 12; MACULAR DEGENERATION, AGE-RELATED, 12, SUSCEPTIBILITY TO
|CLNDSDB=MedGen:OMIM
|CLNDSDBID=C3151079:613784
|CLNSRC=NCBI override; OMIM Allelic Variant
|CLNSRCID=601470.0001
|COMMON=1
|Disease=Human immunodeficiency virus type 1; Coronary artery disease; Age-related macular degeneration 12; MACULAR DEGENERATION
}}

{{PMID Auto
|PMID=17327408
|Title=Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
|OA=1
}}

{{PMID Auto
|PMID=17672867
|Title=Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease.
|OA=1
}}

{{PMID Auto
|PMID=17705862
|Title=Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.
|OA=1
}}

{{PMID Auto
|PMID=18633131
|Title=Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
|OA=1
}}

{{PMID Auto
|PMID=19066394
|Title=Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
|OA=1
}}

{{PMID Auto
|PMID=20506646
|Title=[CX3CR1 polymorphism in patients with dilated cardiomyopathy].
}}

{{PMID Auto
|PMID=21609242
|Title=Age-related macular degeneration-susceptibility single nucleotide polymorphisms in a han chinese control population.
}}

{{GET Evidence
|gene=CX3CR1
|aa_change=Val281Ile
|aa_change_short=V281I
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3732379
|n_genomes=1
|n_genomes_annotated=0
|n_haplomes=1
|n_articles=0
|n_articles_annotated=0
|nblosum100=-4
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=24287500
|Title=Prospective Study of Common Variants in CX3CR1 and Risk of Macular Degeneration: Pooled Analysis From 5 Long-term Studies
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}