{{Rsnum
|rsid=3738919
|Gene=ITGAV
|Chromosome=2
|position=186656533
|Orientation=plus
|GMAF=0.2107
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=ITGAV
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 8.0 | 46.0 | 46.0
| HCB | 0.7 | 10.2 | 89.1
| JPT | 2.7 | 15.9 | 81.4
| YRI | 0.7 | 27.9 | 71.4
| ASW | 1.8 | 29.8 | 68.4
| CHB | 0.7 | 10.2 | 89.1
| CHD | 0.0 | 9.3 | 90.7
| GIH | 12.9 | 37.6 | 49.5
| LWK | 0.9 | 25.7 | 73.4
| MEX | 5.2 | 27.6 | 67.2
| MKK | 5.2 | 34.2 | 60.6
| TSI | 10.8 | 45.1 | 44.1
| HapMapRevision=28
}}
[[rs3738919]], a SNP located in the [[ITGAV]] gene, was identified in a European study to be associated with [[rheumatoid arthritis]] (RA). {{PMID|17615072|OA=1
}}

The risk allele for [[rs3738919]] is the more common allele, (C). For the three European Caucasian populations studied (372 RA patients + 330 controls), and combining the (C;C) and (A;C) genotypes in comparison to the (A;A) genotype, the odds ratio for RA = 1.94 (CI: 1.3â€“2.9, p = 0.002). There was no significant difference in RA risk between those carrying one or two (C) alleles. {{PMID|17615072|OA=1
}}

An editorial about this finding has been published. {{PMID|18001496|OA=1
}}

{{PMID Auto
|PMID=19818132
|Title=The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}