{{Rsnum
|rsid=3740878
|Gene=EXT2
|Chromosome=11
|position=44236252
|Orientation=minus
|GMAF=0.2874
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=EXT2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 55.8 | 31.9 | 12.4
| HCB | 40.0 | 40.0 | 20.0
| JPT | 42.0 | 42.0 | 16.1
| YRI | 84.4 | 14.3 | 1.4
| ASW | 73.7 | 24.6 | 1.8
| CHB | 40.0 | 40.0 | 20.0
| CHD | 28.4 | 53.2 | 18.3
| GIH | 42.6 | 41.6 | 15.8
| LWK | 92.7 | 7.3 | 0.0
| MEX | 28.6 | 48.2 | 23.2
| MKK | 85.9 | 13.5 | 0.6
| TSI | 60.8 | 32.4 | 6.9
| HapMapRevision=28
}}rs3740878 increases susceptibility to Type II Diabetes 1.26 times for heterozygotes (AG) and 1.46 times for homozygotes (AA) {{PMID|17293876}}

{{PMID Auto
|PMID=17786204
|Title=Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.
|OA=1
}}

{{PMID Auto
|PMID=18443202
|Title=Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.
|OA=1
}}

{{PMID Auto
|PMID=18461161
|Title=Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.
|OA=1
}}

{{PMID Auto
|PMID=18544707
|Title=Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.
|OA=1
}}

{{PMID Auto
|PMID=18556337
|Title=Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).
|OA=1
}}

{{PMID Auto
|PMID=18633108
|Title=Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.
|OA=1
}}

{{PMID Auto
|PMID=18689899
|Title=Exchangeable models of complex inherited diseases.
|OA=1
}}

{{PMID Auto
|PMID=19008344
|Title=Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.
|OA=1
}}

{{PMID Auto
|PMID=19401414
|Title=Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
|OA=1
}}

{{PMID Auto
|PMID=21278902
|Title=Genetic risk profiling for prediction of type 2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=22377712
|Title=Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography.
}}

{{PMID Auto
|PMID=23052945
|Title=Association between variants of EXT2 and type 2 diabetes: a replication and meta-analysis
}}

{{PMID Auto
|PMID=25207843
|Title=Impact of variants of the EXT2 gene on Type 2 diabetes and its related traits in the Chinese han population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}