{{Rsnum
|rsid=3740955
|Gene=RAG1
|Chromosome=11
|position=36574050
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.4091
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=RAG1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 42.5 | 38.9 | 18.6
| HCB | 2.9 | 32.1 | 65.0
| JPT | 4.4 | 34.5 | 61.1
| YRI | 5.4 | 30.6 | 63.9
| ASW | 8.8 | 36.8 | 54.4
| CHB | 2.9 | 32.1 | 65.0
| CHD | 9.2 | 42.2 | 48.6
| GIH | 22.8 | 52.5 | 24.8
| LWK | 10.0 | 41.8 | 48.2
| MEX | 15.5 | 43.1 | 41.4
| MKK | 16.8 | 54.2 | 29.0
| TSI | 39.2 | 46.1 | 14.7
| HapMapRevision=28
}}

{{Venter SNP
|rsid=3740955
|allele=G
|frequency=0.405
|uid=1103649659129
|type=heterozygous_SNP
|hugo=RAG1
|ensembl gene=ENSG00000166349
|ensembl transcript=ENST00000299440
|sift=TOLERATED
|disease=Defects in RAG1 are a cause of Omenn syndrome (OS) (MIM:603554). OS is a severe immunodeficiency characterized by the presence of activated, anergic, oligoclonal T cells, hypereosinophilia, and high IgE levels.
}}

{{ neighbor
| rsid = 28933393
| distance = 280
}}

{{GET Evidence
|gene=RAG1
|aa_change=His249Arg
|aa_change_short=H249R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs3740955
|overall_frequency_n=5043
|overall_frequency_d=10758
|overall_frequency=0.468767
|n_genomes=43
|n_genomes_annotated=0
|n_haplomes=61
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=1
|autoscore=2
|n_web_uneval=2
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}