{{Rsnum 
|rsid = 3741981
|Gene = OAS1
|geno1 = (A;A)
|geno2 = (A;G)
|geno3 = (G;G)
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|Chromosome=12
|position=112911065
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Status=Merged
|Merged=1131454
|Gene_s=OAS1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 30.1 | 53.1 | 16.8
| HCB | 32.1 | 44.5 | 23.4
| JPT | 42.5 | 48.7 | 8.8
| YRI | 1.4 | 18.8 | 79.9
| ASW | 10.5 | 38.6 | 50.9
| CHB | 32.1 | 44.5 | 23.4
| CHD | 33.9 | 50.5 | 15.6
| GIH | 28.7 | 49.5 | 21.8
| LWK | 2.7 | 17.3 | 80.0
| MEX | 44.8 | 41.4 | 13.8
| MKK | 1.3 | 28.4 | 70.3
| TSI | 17.6 | 53.9 | 28.4
| HapMapRevision=28
}}

{{PMID|16644715}} Was investigated for a diabetes association, but seemed to have none.

{{PMID|17092260}} suggests it or a neighbor may be involved in [[multiple sclerosis]]

{{omim
|id=164350
|desc=2-PRIME,5-PRIME-@OLIGOADENYLATE SYNTHETASE 1; OAS1
|rsnum=3741981
}}

{{PMID Auto
|PMID=19956105
|Title=Reassessment of the type I diabetes association of the OAS1 locus
|OA=1
}}

{{PMID Auto
|PMID=20079393
|Title=2'-5'-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine
|OA=1
}}

{{PMID Auto
|PMID=22710942
|Title=Evaluate the relationship between polymorphisms of OAS1 gene and susceptibility to chronic hepatitis C with high resolution melting analysis
}}

{{PMID Auto
|PMID=25205466
|Title=Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}