{{Rsnum
|rsid=3746444
|Gene=MYH7B
|Chromosome=20
|position=34990448
|Orientation=minus
|GMAF=0.1814
|Gene_s=MIR499A,MIR499B,MYH7B
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{PMID|18634034}} [[microRNA]] 1,009 breast cancer cases and 1,093 controls in a population of Chinese women
*[[rs3746444]] in [[hsa-mir-499]] A>G OR 1.25; 95% CI, 1.02-1.51
{{PMID Auto
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|Title=A Functional Genetic Variant in microRNA-196a2 Is Associated with Increased Susceptibility of Lung Cancer in Chinese.
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{{PMID Auto
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|Title=Functional variant in microRNA-196a2 contributes to the susceptibility of congenital heart disease in a Chinese population
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|Title=Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases
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|Title=Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy
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|Title=Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck
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{{PMID Auto
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|Title=Genetic variation in microRNA genes and prostate cancer risk in North Indian population
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|Title=Association Study of Common Genetic Variants in Pre-microRNAs in Patients with Ulcerative Colitis
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{{PMID Auto
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|Title=Association Between Common Genetic Variants in Pre-microRNAs and Gastric Cancer Risk in Japanese Population
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{{PMID Auto
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|Title=Genetic study of two single nucleotide polymorphisms within corresponding microRNAs and susceptibility to tuberculosis in a Chinese Tibetan and Han population
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{{PMID Auto
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|Title=Association Between Two Genetic Variants in miRNA and Primary Liver Cancer Risk in the Chinese Population
|OA=1
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{{PMID Auto
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|Title=Association between SNPs in pre-miRNA and risk of chronic obstructive pulmonary disease
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{{PMID|19617315|OA=1
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{{PMID|20428464|OA=1
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{{PMID|20520619}} Common genetic variants in pre-microRNAs and risk of gallbladder cancer in North Indian population.

{{PMID|20845080}} Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus.

{{PMID|21181275}} Association study of single nucleotide polymorphisms in pre-miRNA and rheumatoid arthritis in a Han Chinese population.

{{PMID|21319225}} Common genetic polymorphisms in pre-microRNAs and risk of cervical squamous cell carcinoma.

{{PMID|21345130}} Investigative role of pre-microRNAs in bladder cancer patients: a case-control study in North India.

{{PMID|21663520}} Association between single-nucleotide polymorphisms in pre-miRNAs and the risk of asthma in a Chinese population.

{{PMID|21713406}} Association between two single nucleotide polymorphisms at corresponding microRNA and schizophrenia in a Chinese population.

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{{PMID|22019503}} Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population.

{{PMID|22159951}} Polymorphisms of miRNAs genes are associated with the risk and prognosis of coronary artery disease.

{{PMID|22311030}} Association of the microRNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population.

{{PMID Auto
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|Title=Association of pre-miRNA-146a rs2910164 and pre‑miRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis
}}

{{PMID Auto
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|Title=Hsa-miR-499 rs3746444 Polymorphism Contributes to Cancer Risk: A Meta-Analysis of 12 Studies
|OA=1
}}

{{PMID Auto
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|Title=The association between common genetic variant of microRNA-499 and cancer susceptibility: a meta-analysis
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{{PMID Auto
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|Title=The Association between Two Common Polymorphisms in MicroRNAs and Hepatocellular Carcinoma Risk in Asian Population
|OA=1
}}

{{PMID Auto
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|Title=Association between Genetic Variants in Pre-MicroRNAs and Survival of Early-Stage NSCLC
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{{PMID Auto
|PMID=23219900
|Title=Pre-microRNA variants predict HPV16-positive tumors and survival in patients with squamous cell carcinoma of the oropharynx
|OA=1
}}

{{PMID Auto
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|Title=Polymorphisms of microRNA Sequences or Binding Sites and Lung Cancer: A Meta-Analysis and Systematic Review
|OA=1
}}

{{PMID Auto
|PMID=23679271
|Title=Positive Association Between miR-499A&gt;G and Hepatocellular Carcinoma Risk in a Chinese Population
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{{PMID Auto
|PMID=23728616
|Title=Association between genetic variants in pre-miRNA and colorectal cancer risk in a Chinese population
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{{PMID Auto
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|Title=Association of mir-499 and mir-149 Polymorphisms with Cancer Risk in the Chinese Population: Evidence from Published Studies
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|Title=A functional polymorphism in the miR-146a gene is associated with the risk of childhood acute lymphoblastic leukemia: a preliminary report
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{{PMID Auto
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|Title=An A/G polymorphism rs3746444 in miR-499 is associated with increased cancer risk: a meta-analysis
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{{PMID Auto
|PMID=24102488
|Title=Meta-analysis of pre-miRNA polymorphisms association with susceptibility to autoimmune diseases
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{{PMID Auto
|PMID=24107911
|Title=Association of the hsa-mir-499 (rs3746444) Polymorphisms with Gastric Cancer Risk in the Chinese Population
}}

{{PMID Auto
|PMID=24136745
|Title=Association between microRNA genetic variants and susceptibility to colorectal cancer in Chinese population
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{{PMID Auto
|PMID=23791656
|Title=Three common functional polymorphisms in microRNA encoding genes in the susceptibility to hepatocellular carcinoma: a systematic review and meta-analysis
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{{PMID Auto
|PMID=24194751
|Title=Associations of miR-499 and miR-34b/c Polymorphisms with Susceptibility to Hepatocellular Carcinoma: An Evidence-Based Evaluation
|OA=1
}}

{{PMID Auto
|PMID=24254303
|Title=Two functional polymorphisms in microRNAs and lung cancer risk: a meta-analysis
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{{PMID Auto
|PMID=24258110
|Title=Quantitative assessment of the association between microRNA-499 rs3746444 A/G polymorphism and cancer risk
}}

{{PMID Auto
|PMID=24301908
|Title=miR-499A&gt;G rs3746444 and miR-146aG&gt;C expression and hepatocellular carcinoma risk in the Chinese population
}}

{{PMID Auto
|PMID=24327058
|Title=MicroRNA-499 rs3746444 Polymorphism and Autoimmune Diseases Risk: A Meta-Analysis
}}

{{PMID Auto
|PMID=24413317
|Title=MicroRNA sequence polymorphisms and the risk of different types of cancer
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{{PMID Auto
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|Title=A common variant in pre-miR-146 is associated with coronary artery disease risk and its mature miRNA expression
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{{PMID Auto
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|Title=Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a, miR-149 and miR-499 with Colorectal Cancer Susceptibility
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|Title=Non-coding RNAs-related polymorphisms in pediatric acute lymphoblastic leukemia susceptibility
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|Title=Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population.
}}

{{PMID Auto
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|Title=The association between hsa-miR-499 T>C polymorphism and cancer risk: a meta-analysis.
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{{PMID Auto
|PMID=22922391
|Title=Hsa-miR-499 polymorphism (rs3746444) and cancer risk: a meta-analysis of 17 case-control studies.
}}

{{PMID Auto
|PMID=22970328
|Title=Association of microRNA-499 rs3746444 polymorphism with cancer risk: evidence from 7188 cases and 8548 controls.
|OA=1
}}

{{PMID Auto
|PMID=23001871
|Title=Association of the miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with gastric cancer risk and survival in the Korean population.
}}

{{PMID Auto
|PMID=23053947
|Title=miR-499 rs3746444 polymorphism is associated with cancer development among Asians and related to breast cancer susceptibility.
}}

{{PMID Auto
|PMID=23292097
|Title=Effects of common polymorphisms rs2910164 in miR-146a and rs3746444 in miR-499 on cancer susceptibility: a meta-analysis.
}}

{{PMID Auto
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|Title=Effects of common polymorphism rs11614913 in Hsa-miR-196a2 on lung cancer risk.
|OA=1
}}

{{PMID Auto
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|Title=Association of microRNAs genes polymorphisms with rheumatoid arthritis in Egyptian female patients.
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|Title=Identification of miR-423 and miR-499 Polymorphisms on Affecting the Risk of Hepatocellular Carcinoma in a Large-Scale Population
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{{PMID Auto
|PMID=24039706
|Title=The associations of single nucleotide polymorphisms in miR-146a, miR-196a and miR-499 with breast cancer susceptibility
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{{PMID Auto
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|Title=Genetic Polymorphism of miR-196a as a Prognostic Biomarker for Early Breast Cancer
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{{PMID Auto
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|Title=Genetic variants of MicroRNA-related genes in susceptibility and prognosis of end-stage renal disease and renal allograft outcome among north Indians
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{{PMID Auto
|PMID=25074528
|Title=rs3746444 Polymorphism and Susceptibility to Hepatocellular Carcinoma: Evidence from Published Studies
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{{PMID Auto
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|Title=Comprehensive Review of Genetic Association Studies and Meta-analysis on miRNA polymorphisms and rheumatoid arthritis and systemic lupus erythematosus susceptibility
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{{PMID Auto
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{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}